Yohimbine has been one of the most popular supplements for years. It’s typically used as a fat loss and appetite suppression aid.*
What is Yohimbine?
Yohimbine is a naturally occurring alkaloid found within the bark of the yohimbe tree (Pausinystalia yohimbe) indigenous to central and western Africa.
What is Yohimbine Typically Used For?
- Fat Loss*
- Appetite Control*
What Does Yohimbine Do?
Yohimbine acts as a central nervous stimulant, activating the body’s “fight or flight” response, causing an increase in levels of two catecholamines -- noradrenaline and adrenaline.
Catecholamines can bind to the adrenergic receptors on fat cells and either kick start fat burning or shut it off.
You see, fat cells have two types of adrenergic receptors:
- Alpha receptors -- suppress fat burning
- Beta receptors -- support fat burning
When these catecholamines bind to the alpha receptors, fat burning is stunted. However, when they bind to beta receptors, the adipocyte “unlocks” (in a manner of speaking), unloading its stored fatty acids into the bloodstream where they can then be picked up and burned for energy.*
The problem is that we don’t really get to choose to which receptors our catecholamines bind. And, on top of that, some regions of fat on the body tend to have a greater density of alpha receptors than beta receptors. FYI, these are usually the areas referred to as “stubborn fat.”
Seeing that yohimbine has a high affinity for alpha-2 adrenergic receptors, it can bind to them, thereby allowing more catecholamines available to bind to beta receptors and encourage fat burning.
In other words, yohimbine helps stop fat cells from resisting fat burning.
Supports Fat Loss
Yohimbine’s ability to antagonize (inhibit) alpha-2 adrenergic receptors should support fat loss, and, indeed, there are several studies noting that supplementation with yohimbine does help reduce body fat.*
Yohimbine Hydrochloride 2.5mg